PP77 Phytochemical characterization of Ocotea quixos essential oil by Gas-Mass Chromatography (GC-MS): Study of antidepressant and anxiolytic activity
DOI:
https://doi.org/10.3407/rpn.v6i1pp77Keywords:
Mental disorders, anxiety, antidepressants, phytochemical analysis, anxiolytic, essential oil, Ocotea quixos, behavioral tests, chemical composition, depression.Abstract
In this study, the anxiolytic and antidepressant activity of the methanolic extract (EM) and essential oil of Ocotea quixos (family Lauraceae) was evaluated in a murine model with male CD-1 mice, using behavioral tests: open field, exploratory cylinder, elevated plus maze, and forced swim test. The results suggest that the methanolic extract (EM) could have antidepressant activity, although more research is needed.
References
[1] BRAUND, T. A., et al. (2021). Antidepressant side effects and their impact on treatment outcome in people with major depressive disorder: An iSPOT-D report. *Translational Psychiatry*, 11: 417. [DOI]
[2] EBRAHIMI, H., et al. (2022). The effects of lavender and chamomile essential oil inhalation aromatherapy on depression, anxiety and stress in older community-dwelling people: A randomized controlled trial. *Explore*, 18(3): 272–278. [DOI]
[3] RADICE, M., et al. (2016). *Ocotea quixos* essential oil: A systematic review about ethno‑medicinal uses, phytochemistry and biological activity. Conference paper. [DOI]
Downloads
Published
Issue
Section
Categories
License
Copyright (c) 2026 Karla VALDERRAMA CARDOZO, Silvia Laura GUZMÁN-GUTIERRES, Juan Camilo VARGAS GALLEGO, Jhonattan NAVARRO SANTANILLA, Jhon Ironzi MALDONADO RODRÍGUEZ

This work is licensed under a Creative Commons Attribution 4.0 International License.
License Terms
The Creative Commons Attribution License (CC BY 4.0) allows users to copy, distribute and transmit an article and adapt the article and make commercial use of the article. The CC BY license permits commercial and non-commercial re-use of an open access article, as long as the author is properly attributed.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
- You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
- No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity.

