Revista Productos Naturales
type: channel
description: The Revista Productos Naturales (RPN) (ISSN 1916-2413) is an open-access electronic journal dedicated to the specialized dissemination of scientific research. It publishes fundamental and applied research articles with significant contributions to the science, technology, and industry of natural products of plant, animal, or microbial origin, including terrestrial and marine organisms. The Revista Productos Naturales is completely free for both authors and readers. There are no submission, processing, publication, or access fees, ensuring that scientific knowledge remains available to everyone without economic barriers. To ensure long-term preservation and archiving, the journal is deposited in multiple digital preservation systems, including CLOCKSS, LOCKSS, Internet Archive, and PKP PN. These mechanisms guarantee continuous accessibility, integrity, and durability of the published content.
publisher: Nozomi Science
language: en
publication name: Revista Productos Naturales
issn: 1916-2413
copyright: License Terms The Creative Commons Attribution License (CC BY 4.0) allows users to copy, distribute and transmit an article and adapt the article and make commercial use of the article. The CC BY license permits commercial and non-commercial re-use of an open access article, as long as the author is properly attributed. You are free to: Share — copy and redistribute the material in any medium or format for any purpose, even commercially. Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits. Notices: You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation. No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity.
items: PO42 Mini-Review On Kalanchoe spp.: Phytochemical Composition, Biological Properties, and Research Perspectives in Colombia
items: PO9 Road to Strengthening Research in Natural Products. View from the Technological University of Uruguay
items: CP2 Small Organic Molecules from Natural Sources: The End of an Era?
items: Premio “Juan Martínez Valderrama”
items: ED Editorial del I Congreso Colombiano de Productos Naturales
items: PI-3 Committees of the 1st Colombian Congress of Natural Products (2025)
items: PI-2 Agradecimientos a nuestros patrocinadores
items: PI-1 Nota histórica del cambio de nombre del Congreso Colombiano de Fitoquímica al Congreso Colombiano de Productos Naturales
items: PP89 Antioxidant activity of Ganoderma lucidum evaluated by electrochemical assays
items: PP62 Study of the Bioactive Compounds of Apis mellifera honey obtained from Eugenia stipitata (Arazá).
items: PP56 Chemical properties of Apis mellifera honey (Hymenoptera: Apidae) produced in the Colombian Amazon.
items: PP28 Obtaining functional cookies from copoazú (Theobroma grandiflorum) pulp
items: PP35 Antihypertensive potential of extracts pulp Theobroma grandiflorum amazonian fruit
items: PP94 Electrochemical determination of the antioxidant activity of Laetiporus sulphureus
items: PP77 Phytochemical characterization of Ocotea quixos essential oil by Gas-Mass Chromatography (GC-MS): Study of antidepressant and anxiolytic activity
items: PP68 EVALUACIÓN DE LA ACTIVIDAD ANTIOXIDANTE Y ANÁLISIS DE METABOLITOS EN OCHO ESPECIES DE MACROMICETOS AMAZÓNICOS DE LOS ÓRDENES POLYPORALES Y AGARICALES MEDIANTE GC-MS Y LC-MS.
items: https://www.nozomiscience.org/index.php/rpn/en/article/view/10818
items: PO57 Untargeted Metabolomic Analysis by LC-MS for the differentiation of arazá (Eugenia stipitata) subspecies.
items: PP7 Evaluation of the effect of solvent on the content of phenolic compounds and antioxidant activity in fresh and dried peel of honey gold pineapple and India Caqueteña.
items: PP95 Extraction and characterization of bioactive compounds in fruit residues from the Colombian Amazon
items: PP14 Exploitation of copoazú (Theobroma grandiflorum) seed husk: Evaluation of bioactive compounds and antioxidant activity
items: PP21 Effect of the Spray Drying Process on the Encapsulation of Amazonian Fruit Pulp Enriched with cupuacu (Theobroma grandiflorum) Seed Extract
items: https://www.nozomiscience.org/index.php/rpn/en/article/view/10813
items: PO60 Extraction of antioxidants from chontaduro (Bactris gasipaes) peel using supercritical carbon dioxide
items: PO59 Photoprotective activity of extracts from native Amazonian plants: an exploratory study
items: CP8 Biocommunicators for parasitic weed control: honeypot strategy
items: PP41 Antifungal Activity of Ethanolic Extract of Ripe Seeds from Azadirachta indica against Pestalotia sp in Coffee Leaf – Experimental Farm Pueblo Bello, Cesar
items: PP55 Influence of microencapsulation on the stability and evaluation of the antimicrobial activity of essential oils from the Lamiaceae family
items: PO22 Larvicidal effect of hexane and ethyl acetate extracts of Austroeupatorium inulifolium on fourth-instar larvae of Aedes aegypti
items: PP36 Estudio del Potencial Inhibitorio sobre Lipasa Pancréatica de Algunos Componentes Químicos Provenientes de Piper asperiusculum (Piperaceae)

PO42 Mini-Review On Kalanchoe spp.: Phytochemical Composition, Biological Properties, and Research Perspectives in Colombia
type: item
description: The species Kalanchoe pinnata has been widely studied for its phytochemical and bioactive properties, including antioxidant, anti-inflammatory, and potential anticancer activity [1]. Through this mini-review, 33 articles published in scientific journals such as Revista Brasileira de Farmacognosia, BMC, SciELO, Rev. Colomb. Cienc. Quím., South Florida Journal of Development, and Natural Product Communications between 2015 and 2024 were analyzed, aiming to consolidate knowledge about this plant and its application in health.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: kalanchoe pinnata
  topic: keywords
subject: extracto
  topic: keywords
subject: cáncer
  topic: keywords
creator: NINA MARIA SANCHEZ RAMIREZ
creator: Jhon Fredy Castañeda Gómez
creator: Yurani Aleyda Cuetumbo Aposta
creator: María Alejandra Pulido Zabaleta
creator: Natalia Santofimio Gaviria
rights: Copyright (c) 2025 Nina María SANCHEZ RAMIREZ, Jhon Fredy Castañeda Gómez, Yurani Aleyda Cuetumbo Aposta, María Alejandra Pulido Zabaleta, Natalia Santofimio Gaviria https://creativecommons.org/licenses/by/4.0
date: 2025-06-30
publication date: 2025-06-30
starting page: 153
ending page: 156
doi: 10.3407/0eqw3g96

PO9 Road to Strengthening Research in Natural Products. View from the Technological University of Uruguay
type: item
description: In Uruguay, where Montevideo concentrates much of the educational and scientific infrastructure, the expansion of areas such as natural products in institutions in the interior has been key to regional development. This is reflected in impactful projects, such as clinics, theses, and workshops, that explore various aspects of these products. These projects have allowed students and professionals to become involved in the research and development of new products, fostering knowledge exchange between different regions.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Licenciatura en Análisis Alimentario
  topic: keywords
subject: Productos naturales
  topic: keywords
subject: Universidad Tecnológica del Uruguay.
  topic: keywords
creator: María Rossina Figliolo Mederos
creator: Jhonatan Cardozo
creator: Annabela Estévez
rights: Copyright (c) 2025 María Rossina Figliolo Mederos, Jhonatan Cardozo, Annabela Estévez Onetto https://creativecommons.org/licenses/by/4.0
date: 2025-05-17
publication date: 2025-05-17
starting page: 54
ending page: 56
doi: 10.3407/d27ka069

CP2 Small Organic Molecules from Natural Sources: The End of an Era?
type: item
description: The multinational pharmaceutical industry (Big Pharma) has transitioned towards the development of macromolecules through heterologous production platforms, aiming to protect substantial financial investments associated with developing new therapies.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Natural Products
  topic: keywords
subject: Drug Discovery
  topic: keywords
subject: Therapeutic Innovation
  topic: keywords
creator: Guillermo León Montoya Peláez
rights: Copyright (c) 2025 Guillermo León Montoya Peláez https://creativecommons.org/licenses/by/4.0
date: 2025-05-20
publication date: 2025-05-20
starting page: 10
ending page: 11
doi: 10.3407/6pdrpq94

Premio “Juan Martínez Valderrama”
type: item
description: El Premio Juan Martínez Valderrama ha sido instaurado en el marco del I Congreso Colombiano de Productos Naturales (2025) con el firme propósito de reconocer la excelencia académica y científica de los participantes a mejores posters y presentaciones orales en las categorías: Senior, Posgrado y Pregrado. Este galardón honra la memoria del distinguido investigador Juan Martínez Valderrama (Febrero 24 de 1944 – Enero 4 de 2024), cuyo legado en el campo de los productos naturales ha sido fundamental para el avance de la ciencia en Colombia y en el mundo.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: premio
  topic: keywords
subject: Juan Martínez Valderrama
  topic: keywords
subject: distinción académica
  topic: keywords
creator: José Hipólito Isaza Martienz
rights: Copyright (c) 2025 José Hipólito Isaza Martínez https://creativecommons.org/licenses/by/4.0
date: 2025-05-10
publication date: 2025-05-10
starting page: xiv
ending page: xv
doi: 10.3407/rpn.v6i1pJMV1

ED Editorial del I Congreso Colombiano de Productos Naturales
type: item
description: En el año 2025, con gran orgullo y satisfacción, nos complace anunciar la realización del "I Congreso Colombiano de Productos Naturales". Esta nueva denominación representa un paso adelante en la evolución del congreso, abriendo sus puertas a una gama más amplia de temas y enfoques relacionados con los productos naturales. El congreso sigue siendo un espacio para el intercambio de ideas innovadoras, la presentación de investigaciones de vanguardia y la creación de redes de colaboración entre académicos, empresarios, profesionales y estudiantes.
subject: Editorial
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Productos naturales
  topic: keywords
subject: metabolitos especializados
  topic: keywords
creator: José Hipólito Isaza Martienz
rights: Copyright (c) 2025 José Hipólito Isaza Martínez https://creativecommons.org/licenses/by/4.0
date: 2025-05-12
publication date: 2025-05-12
starting page: 1
ending page: 5
doi: 10.3407/10.3407/rpn.v6i1ed

PI-3 Committees of the 1st Colombian Congress of Natural Products (2025)
type: item
description: The document outlines the committees for the I Colombian Congress on Natural Products scheduled for 2025, detailing the members of the Organizing Committee, Scientific Committee, and Editorial Committee, including their affiliations and roles.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: comité científico
  topic: keywords
subject: comité organizador
  topic: keywords
subject: equipo logístico
  topic: keywords
creator: José Hipólito Isaza Martienz
rights: Copyright (c) 2025 José Hipólito Isaza Martínez https://creativecommons.org/licenses/by/4.0
date: 2025-05-08
publication date: 2025-05-08
starting page: viii
ending page: xiii
doi: 10.3407/rpn.v6i1com1

PI-2 Agradecimientos a nuestros patrocinadores
type: item
description: El Comité Organizador del “I Congreso Colombiano de Productos Naturales (2025)” desea expresar su más sincero agradecimiento a las empresas que han hecho posible la realización de este evento. Su apoyo ha sido fundamental para llevar a cabo este congreso y promover el desarrollo y conocimiento de los productos naturales en Colombia.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: patrocinadores
  topic: keywords
subject: sponsors
  topic: keywords
creator: José Hipólito Isaza Martienz
rights: Copyright (c) 2025 José Hipólito Isaza Martínez https://creativecommons.org/licenses/by/4.0
date: 2025-05-08
publication date: 2025-05-08
starting page: iv
ending page: vii
doi: 10.3407/rpn.v6i1sp1

PI-1 Nota histórica del cambio de nombre del Congreso Colombiano de Fitoquímica al Congreso Colombiano de Productos Naturales
type: item
description: Con el fin de honrar esta diversidad de fuentes de productos naturales, los participantes del XIV Congreso Colombiano de Fitoquímica decidieron por consenso cambiar el nombre del evento a "Congreso Colombiano de Productos Naturales". Este cambio refleja la ampliación del enfoque del congreso, abarcando no solo la fitoquímica, sino también otros productos naturales y las nuevas tendencias como las ciencias ómicas y la educación.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Congreso Colombioano
  topic: keywords
subject: Productos Naturales
  topic: keywords
subject: Cambio de Nombre
  topic: keywords
creator: José Hipólito Isaza Martienz
rights: Copyright (c) 2025 José Hipólito Isaza Martínez https://creativecommons.org/licenses/by/4.0
date: 2025-05-12
publication date: 2025-05-12
starting page: i
ending page: iii
doi: 10.3407/rpn.v6i1nom1

PP89 Antioxidant activity of Ganoderma lucidum evaluated by electrochemical assays
type: item
description: This study investigated the antioxidant activity and electrochemical behavior of the fungus G. lucidum using electrochemical techniques. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were performed in a three-electrode system, utilizing glassy carbon as the working electrode, Ag/AgCl as the reference electrode, and a platinum rod as the auxiliary electrode, in a 0.02 M acetate buffer solution (pH 5.0). G. lucidum exhibited antioxidant activity, suggesting an electroactive chemical composition. Furthermore, the Epa for G. lucidum was more anodic with respect to the standards ascorbic acid and gallic acid
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Antioxidant activity
  topic: keywords
subject: electrochemical techniques
  topic: keywords
creator: Jaime Fernando Martínez Suárez
creator: Lisette Dyanna Ruiz Bravo
creator: Olga Lucía Benavides Calvache
rights: Copyright (c) 2025 Jaime Fernando Martínez Suárez, Lisette Dyanna Ruiz Bravo, Olga Lucía Benavides Calvache https://creativecommons.org/licenses/by/4.0
date: 2025-07-03
publication date: 2025-07-03
starting page: 480
ending page: 481
doi: 10.3407/8gbcn275

PP62 Study of the Bioactive Compounds of Apis mellifera honey obtained from Eugenia stipitata (Arazá).
type: item
description: In the present study, five types of honey were evaluated: two containing Arazá floral nectar (Arazá honey) (M001, M002) collected in the department of Caquetá, and three others from southern Colombia. The characteristics of these honeys were evaluated by examining their physicochemical properties, color, and their constituent compounds, which were confirmed by GC-MS analysis. Fifteen phenolic compounds were detected in honey sample M002, the most abundant phenolic compounds tentatively detected were 3,4-dihydroxybenzoic acid, salicylic acid, caffeic acid, chlorogenic acid, pcumaric acid, ferulic acid, gallic acid, syringic acid, isorhamnetin, kaempferol, luteolin, naringenin, pinobanksin, quercetin and rutin
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Eugenia stipitata
  topic: keywords
subject: Apis mellifera
  topic: keywords
subject: bioactive compounds
  topic: keywords
creator: Liceth Natalia Cuellar Alvarez
creator: Yina Herrera
creator: Mayrin O. Valencia
creator: Jhon Ironzi Maldonado
creator: Alejandro García Rios
rights: Copyright (c) 2025 Liceth Natalia Cuellar Alvarez, Yina Herrera, Mayrin O. Valencia, Jhon Ironzi Maldonado, Alejandro García Rios https://creativecommons.org/licenses/by/4.0
date: 2025-07-24
publication date: 2025-07-24
starting page: 399
ending page: 401
doi: 10.3407/ky3t7v10

PP56 Chemical properties of Apis mellifera honey (Hymenoptera: Apidae) produced in the Colombian Amazon.
type: item
description: This study aimed to evaluate the physicochemical parameters, chemical composition, and antioxidant and antimicrobial activities of honeys collected from five localities in Caquetá. Physicochemical parameters were considered. Additionally, antioxidant properties were evaluated using the DPPH (9.0% - 18.0% inhibition), FRAP (130.0 - 450.0 μmol Fe²⁺/kg of honey), and ORAC (1300 - 4000 μmol TE/g of honey) methods. Antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was also analyzed, yielding promising results that support the therapeutic potential of honey produced in the Colombian Amazon.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Biochemical composition
  topic: keywords
subject: apiculture
  topic: keywords
subject: food quality
  topic: keywords
subject: Apis mellifera
  topic: keywords
creator: Liceth Natalia Cuellar Alvarez
creator: Mayrin O. Valencia
creator: Jhon Ironzi Maldonado
creator: Yina HERRERA
creator: Alejandro Garcia Rios
rights: Copyright (c) 2025 Liceth Natalia Cuellar Alvarez, Mayrin O. Valencia, Jhon Ironzi Maldonado, Yina HERRERA, Alejandro Garcia Rios https://creativecommons.org/licenses/by/4.0
date: 2025-07-24
publication date: 2025-07-24
starting page: 380
ending page: 382
doi: 10.3407/b5dw2k65

PP28 Obtaining functional cookies from copoazú (Theobroma grandiflorum) pulp
type: item
description: The objective of this study was to develop functional cookies from cupuassu ( Theobroma grandiflorum) pulp, and their physicochemical and sensory properties were evaluated. Sensory analysis was performed with a trained panel of 10 individuals (5 men and 5 women). The treatment that showed the best attributes was that with proportions of (5:20:75) (Sweetener: Ingredients: Pulp). The cookies exhibited a considerable amount of vitamins, such as Vitamin C (6.15 mg/100 g DW). Furthermore, a significantly higher phenolic content was observed in the cookies with the addition of cupuassu pulp (235 mg GAE/100 g).
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Functional foods, Copoazú, Amazonian fruit, Antioxidants, Vitamin C.
  topic: keywords
creator: Liceth Natalia Cuellar Alvarez
rights: Copyright (c) 2025 Liceth Natalia Cuellar Alvarez, Wilson RODRIGUEZ, Gloria M. PALADINES https://creativecommons.org/licenses/by/4.0
date: 2025-07-22
publication date: 2025-07-22
starting page: 277
ending page: 279
doi: 10.3407/k635k930

PP35 Antihypertensive potential of extracts pulp Theobroma grandiflorum amazonian fruit
type: item
description: The objective of this study was to characterize, using liquid chromatography coupled with mass spectrometry analysis, together with the evaluation of the in vitro antihypertensive activity of the pulp of Copoazú fruits. The chromatographic profile of the extract obtained with ethyl acetate indicated the presence of polyphenols such as gallic acid, and other metabolites with biological potential. Likewise, the in vitro antihypertensive activity evaluated through the ACE-I enzyme inhibition assay showed that the extract enriched in ethyl acetate obtained a percentage of inhibition compared to another Amazonian fruit
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Theobroma grandiflorum; antihypertensive activity; polyphenols; Amazonian fruit.
  topic: keywords
creator: Liceth Natalia Cuellar Alvarez
rights: Copyright (c) 2025 Liceth Natalia Cuellar Alvarez, Wilson RODRIGUEZ, Gloria M. PALADINES https://creativecommons.org/licenses/by/4.0
date: 2025-07-21
publication date: 2025-07-21
starting page: 318
ending page: 320
doi: 10.3407/dxzy0542

PP94 Electrochemical determination of the antioxidant activity of Laetiporus sulphureus
type: item
description: The electrochemical behavior and antioxidant activity of L. sulphureus was performed by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). For CV and DPV, a three-electrode system was used: glassy carbon working electrode, Ag/AgCl reference electrode, and platinum auxiliary electrode, using a 0.02 M acetate buffer (pH 5.0). The electrochemical behavior of L. sulphureus showed an irreversible charge transfer process centered at an anodic peak potential (Epa) of 0.52 V. Ascorbic acid presented an Epa of 0.29 V, while gallic acid exhibited two anodic peaks, at 0.41 V and 0.69 V.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Antioxidant activity, electrochemical techniques.
  topic: keywords
creator: Lisette Dyanna Ruiz Bravo
creator: Jaime Fernando Martínez Suárez
creator: Olga Lucía Benavides Calvache
rights: Copyright (c) 2025 Lisette Dyanna Ruiz Bravo, Jaime Fernando Martínez Suárez, Olga Lucía Benavides Calvache https://creativecommons.org/licenses/by/4.0
date: 2025-07-23
publication date: 2025-07-23
starting page: 495
ending page: 496
doi: 10.3407/nm38yx31

PP77 Phytochemical characterization of Ocotea quixos essential oil by Gas-Mass Chromatography (GC-MS): Study of antidepressant and anxiolytic activity
type: item
description: In this study, the anxiolytic and antidepressant activity of the methanolic extract (EM) and essential oil of Ocotea quixos (family Lauraceae) was evaluated in a murine model with male CD-1 mice, using behavioral tests: open field, exploratory cylinder, elevated plus maze, and forced swim test. The results suggest that the methanolic extract (EM) could have antidepressant activity, although more research is needed.
subject: Abstract
  topic: section
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Mental disorders, anxiety, antidepressants, phytochemical analysis, anxiolytic, essential oil, Ocotea quixos, behavioral tests, chemical composition, depression.
  topic: keywords
creator: Karla Valderrama Cardozo
creator: Silvia Laura Guzmán-Gutierrez
creator: Juan Camilo Vargas Gallego
creator: Jhonattan Navarro Santanilla
creator: Jhon Ironzi Maldonado Rodríguez
rights: Copyright (c) 2026 Karla VALDERRAMA CARDOZO, Silvia Laura GUZMÁN-GUTIERRES, Juan Camilo VARGAS GALLEGO, Jhonattan NAVARRO SANTANILLA, Jhon Ironzi MALDONADO RODRÍGUEZ https://creativecommons.org/licenses/by/4.0
date: 2026-01-21
publication date: 2026-01-21
starting page: 501
ending page: 503
doi: 10.3407/rpn.v6i1pp77

PP68 EVALUACIÓN DE LA ACTIVIDAD ANTIOXIDANTE Y ANÁLISIS DE METABOLITOS EN OCHO ESPECIES DE MACROMICETOS AMAZÓNICOS DE LOS ÓRDENES POLYPORALES Y AGARICALES MEDIANTE GC-MS Y LC-MS.
type: item
description: Macromycetes are fungi with visible fruiting bodies that are a valuable source of nutrients and bioactive compounds [1]. Its chemical composition includes fatty acids, vitamins, phenolic compounds, and terpenoids, which possess antioxidant, anti-inflammatory, and antimicrobial properties. These characteristics make them relevant for the prevention of chronic diseases and their possible applications in the pharmaceutical and food industries
subject: Abstract
  topic: section
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: bioactive metabolites
  topic: keywords
subject: wild mushrooms
  topic: keywords
subject: chemical ecology
  topic: keywords
subject: biotechnology
  topic: keywords
subject: bioprospecting
  topic: keywords
creator: Julieth Stephania Cano Manjarres
creator: Laura Marcela Orozco Gasca
creator: Chiara Carazzone
creator: Gerson Dirceu López
creator: Paula Liliana Galeano García
rights: Copyright (c) 2026 Julieth Cano, Laura Orozco, Chiara Carazzone, Gerson Dirceu, Paula Galeano https://creativecommons.org/licenses/by/4.0
date: 2026-01-19
publication date: 2026-01-19
starting page: 417
ending page: 420
doi: 10.3407/rpn.v6i1pp68

https://www.nozomiscience.org/index.php/rpn/en/article/view/10818
type: item
title: PP88 Exploitation of Pineapple Peel Residues, India and Oro Miel Varieties: Extraction of Essential Oils by Hydrodistillation and NADES. Chemical Characterization and Evaluation of Antioxidant Activity
description: In Colombia, approximately 32,700 ha of pineapple are cultivated, generating large amounts of peel waste (1). These peels pose an environmental issue but contain bioactive compounds such as essential oils (EO), valuable in several industries (2). This study focused on EO extraction from Oro miel and Crespa pineapple peels using microwave-assisted hydrodistillation (MAHD) with Natural Deep Eutectic Solvents (NADES). Various NADES were formulated and characterized. Extraction conditions were optimized, and the best ones were applied to MAHD using NADES. Finally, EO were analyzed by GC-MS, revealing differences in volatile profiles between the two pineapple varieties.
subject: Abstract
  topic: section
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Hydrodistillation, NADES, pineapple varieties, GC-MS and residues
  topic: keywords
creator: Monica Gisella Cupitre Mojica
creator: Mayrin Oslany Valencia Sotto
creator: Gloria Paladines Beltrán
creator: Paula Liliana Galeano García
rights: Copyright (c) 2026 Monica Cupitre, Mayrin Valencia, Gloria Magally Paladines Beltrán, Paula Galeano https://creativecommons.org/licenses/by/4.0
date: 2026-01-21
publication date: 2026-01-21
starting page: 477
ending page: 479
doi: 10.3407/rpn.v6i1pp88

PO57 Untargeted Metabolomic Analysis by LC-MS for the differentiation of arazá (Eugenia stipitata) subspecies.
type: item
description: Eugenia stipitata is a perennial tree belonging to the Myrtaceae family that is native to the Amazon rainforest. It was characterized by McVaugh in 1956 based on samples collected in Peru, Brazil, Bolivia, and Colombia.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Eugenia stipitata
  topic: keywords
subject: LC-MS
  topic: keywords
subject: untargeted Metabolomics
  topic: keywords
subject: PLE extraction.
  topic: keywords
creator: Paula Liliana Galeano García
creator: Elena Ibañez
creator: Alejandro Cifuentes
creator: Alberto Valdes
creator: Jose Mendiola
rights: Copyright (c) 2025 Paula Liliana Galeano García, Elena Ibañez, Alejandro Cifuentes, Alberto Valdes, Jose Mendiola https://creativecommons.org/licenses/by/4.0
date: 2025-07-15
publication date: 2025-07-15
starting page: 198
ending page: 200
doi: 10.3407/ar1mem83

PP7 Evaluation of the effect of solvent on the content of phenolic compounds and antioxidant activity in fresh and dried peel of honey gold pineapple and India Caqueteña.
type: item
description: Pineapple (Ananas comosus) processing generates significant agro-industrial waste, mainly peels, accounting for up to 50% of the fruit [1]. These residues may contain more bioactive compounds than the edible portion [3,4]. This study evaluated the effect of solvent (70% methanol and acetone) and peel condition (fresh and dried) in two pineapple varieties [2,5]. Ultrasound-assisted extraction was applied. Dried peels extracted with acetone showed the highest phenolic content and antioxidant activity in the INDIA variety. IR-ATR analysis confirmed functional groups associated with phenolic structures, highlighting the potential for sustainable valorization of these by-products.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Bioactive compounds, phenolic compounds, antioxidant activity, agro-industrial waste.
  topic: keywords
creator: Nathalia Alejandra Venegas Morales
creator: Paula Liliana Galeano García
creator: Gloria Paladines Beltrán
rights: Copyright (c) 2025 Nathalia A. Venegas, Paula Galeano, Gloria Magally Paladines Beltrán https://creativecommons.org/licenses/by/4.0
date: 2025-07-18
publication date: 2025-07-18
starting page: 231
ending page: 234
doi: 10.3407/s8sx8r87

PP95 Extraction and characterization of bioactive compounds in fruit residues from the Colombian Amazon
type: item
description: The agricultural sector generates underutilized plant residues that may pollute the environment [1,2]. This study evaluated peels, husks, and seeds of Myrciaria dubia, Bactris gasipaes, Eugenia stipitata, and Arbutus unedo as sources of bioactive compounds [3]. Ultrasound-assisted extraction was applied to fresh and dried samples using 70% methanol and acetone. Dried peels and husks extracted with acetone showed the highest phenolic content and antioxidant activity. IR-ATR analysis confirmed functional groups associated with phenolics. Results highlight the potential of these by-products for sustainable applications in food and cosmetic industries.
subject: Abstract
  topic: section
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Bioactive compounds
  topic: keywords
subject: IR-ATR spectroscopy
  topic: keywords
subject: Agro-industrial residues
  topic: keywords
subject: Polarity
  topic: keywords
creator: Gloria Paladines Beltrán
creator: Nathalia Alejandra Venegas Morales
creator: Paula Liliana Galeano García
rights: Copyright (c) 2026 Gloria M. Paladines, Nathalia A. Venegas, Paula Galeano https://creativecommons.org/licenses/by/4.0
date: 2026-01-19
publication date: 2026-01-19
starting page: 498
ending page: 500
doi: 10.3407/rpn.v6i1pp95

PP14 Exploitation of copoazú (Theobroma grandiflorum) seed husk: Evaluation of bioactive compounds and antioxidant activity
type: item
description: Cupuaçu (Theobroma grandiflorum) is a valuable Amazonian fruit, whose seeds generate by-products such as the husk, which are often underutilized [1,2]. Given its nutritional potential and similarity to cocoa husk [3], this study evaluated the extraction of bioactive compounds from cupuaçu seed husk using ultrasound-assisted extraction (UAE) and conventional extraction (CE). UAE with 70% ethanol for 75–120 minutes improved the recovery of nutritional compounds, phenolics, flavonoids, and antioxidant activity compared to CE, which required 96 hours [4]. These findings highlight the efficiency of UAE for valorizing agro-industrial residues.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Bioactive compounds, Bioactive compounds, Nutritional compounds, Extraction, ultrasound
  topic: keywords
creator: Gloria Paladines Beltrán
creator: Nathalia Alejandra Venegas Morales
creator: Valentina Vargas Rocha
rights: Copyright (c) 2025 Gloria M. Paladines, Nathalia A. Venegas, Valentina Vargas https://creativecommons.org/licenses/by/4.0
date: 2025-07-19
publication date: 2025-07-19
starting page: 255
ending page: 257
doi: 10.3407/v9kgq786

PP21 Effect of the Spray Drying Process on the Encapsulation of Amazonian Fruit Pulp Enriched with cupuacu (Theobroma grandiflorum) Seed Extract
type: item
description: Cupuassu and açaí are fruits known for their richness in bioactive compounds, although their utilization is limited due to their high perishability and the traditional use of their seeds [1–3]. This study evaluated the optimization of spray drying to encapsulate cupuassu and açaí pulps, incorporating cupuassu seed extract. A central composite design was applied to analyze the effect of three variables on bioactive and physical properties. The optimal conditions (165 °C, 9.6% maltodextrin, 11.3% extract) resulted in high compound retention, good yield, and low moisture content, enhancing the stability of the final product [4,5].
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Bioactive compounds, spray drying, central composite design (CCD), response surface methodology (RSM).
  topic: keywords
creator: Valentina Vargas Rocha
creator: Nathalia Alejandra Venegas Morales
creator: Liceth Natalia Cuellar Álvarez
creator: Andrea Hermosa Otero
creator: Wilson Rodríguez Perez
creator: Gloria Paladines Beltrán
rights: Copyright (c) 2025 Valentina Vargas, Nathalia A. Venegas, Liceth N. Cuellar, Andrea Hermosa, Wilson Rodríguez, Gloria M. Paladines https://creativecommons.org/licenses/by/4.0
date: 2025-07-19
publication date: 2025-07-19
starting page: 276
ending page: 278
doi: 10.3407/w8x8tw43

https://www.nozomiscience.org/index.php/rpn/en/article/view/10813
type: item
title: PO52 Preliminary Phytochemical Evaluation and Antimicrobial Activity Analysis of Extracts Derived from Residual Biomass of Coffee Cherry and Coffee Parchment Against Microorganisms Associated with the Oral Microbiota
description: Coffee is among the most widely consumed beverages globally, resulting in the generation of substantial volumes of plant-based waste. During the harvesting and processing stages of coffee beans, significant amounts of by-products are produced, notably coffee cherry and coffee parchment. If not properly managed, these residues can become a major source of environmental pollution.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Coffee cherry
  topic: keywords
subject: Parchment coffee
  topic: keywords
subject: Coffee arabica
  topic: keywords
subject: Lactobacillus acidophilus
  topic: keywords
subject: Streptococcus mutans
  topic: keywords
subject: Candida albicans
  topic: keywords
subject: Antimocrobial activity
  topic: keywords
subject: Cell viability
  topic: keywords
creator: Luis Gonzalo Sequeda-Castañeda
creator: María Camila Briceño-Chagüí
creator: Yani Leandro Lozada-Poveda
creator: Mayra Alexandra Téllez-Corral
creator: Jean Carlos Villamil-Poveda
creator: Sandra Janeth Gutiérrez-Prieto
rights: Copyright (c) 2025 Luis Gonzalo Sequeda Castañeda, María Camila Briceño-Chagüí , Yani Leandro Lozada-Poveda , Mayra Alexandra Téllez-Corral, Jean Carlos Villamil-Poveda, Sandra Janeth Gutiérrez-Prieto https://creativecommons.org/licenses/by/4.0
date: 2025-07-07
publication date: 2025-07-07
starting page: 183
ending page: 184
doi: 10.3407/dpykbf34

PO60 Extraction of antioxidants from chontaduro (Bactris gasipaes) peel using supercritical carbon dioxide
type: item
description: The "chontaduro" fruit (Bactris gasipaes) is a plant-based product of Amazonian origin that is marketed in several regions of Colombia and is even exported. However, its peel is an agro-industrial byproduct rich in carotenoids—compounds with significant antioxidant activity that are highly valued in the food, nutraceutical, and pharmaceutical industries.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Antioxidants
  topic: keywords
subject: Bactris gasipaes
  topic: keywords
subject: supercritical extraction
  topic: keywords
creator: Carlos Esteban Zapata
creator: Juan David Rivera
creator: Isabel Mejía
creator: Gustavo E. Bolaños
rights: Copyright (c) 2025 Carlos Esteban Zapata, Juan David Rivera, Isabel Mejía, Gustavo E. Bolaños https://creativecommons.org/licenses/by/4.0
date: 2025-07-02
publication date: 2025-07-02
starting page: 207
ending page: 209
doi: 10.3407/rpn.v6i1po43

PO59 Photoprotective activity of extracts from native Amazonian plants: an exploratory study
type: item
description: Extended exposure to solar radiation in humans is currently a public health concern due to the carcinogenic effects of ultraviolet (UV) radiation [1]. One of the most effective strategies to mitigate its effects is the use of photoprotective agents. However, the active ingredients in sunscreens, both chemical and physical UV filters, have raised increasing concern due to their toxicity in humans [2], their impact on marine ecosystems, and their low biodegradability.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Amazonian flora
  topic: keywords
subject: sunscreen
  topic: keywords
subject: photoprotection
  topic: keywords
subject: bioprospection
  topic: keywords
creator: Marcela Piedad Carrillo Bautista
creator: Juliana Erika Cristina Cardona Jaramillo
creator: Gustavo E. Bolaños
rights: Copyright (c) 2025 Marcela Piedad Carrillo Bautista, Juliana Erika Cristina Cardona Jaramillo, Gustavo E. Bolaños https://creativecommons.org/licenses/by/4.0
date: 2025-07-02
publication date: 2025-07-02
starting page: 204
ending page: 206
doi: 10.3407/rpn.v6i1po34

CP8 Biocommunicators for parasitic weed control: honeypot strategy
type: item
description: Parasitic weeds pose a significant threat to agricultural productivity, necessitating the development of sustainable control methods. Traditional herbicides have led to the emergence of resistant weed varieties, underscoring the urgent need for environmentally friendly and effective alternatives.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Parasitic weeds
  topic: keywords
subject: honeypot strategy
  topic: keywords
subject: strigolactones
  topic: keywords
subject: organic synthesis
  topic: keywords
subject: encapsulations
  topic: keywords
creator: Francisco Antonio
creator: Jesús G. Zorrilla
creator: Carlos Rial
creator: Antonio Cala Peralta
creator: Francisco J. Rodríguez-Mejías
creator: Rosa M. Varela
creator: José María González Molinillo
rights: Copyright (c) 2025 Francisco Antonio Macías Domínguez, Jesús G. Zorrilla, Carlos Rial; Antonio Cala Peralta; Francisco J. Rodríguez-Mejías, Rosa María Varela Montoya, José María González Molinillo https://creativecommons.org/licenses/by/4.0
date: 2025-05-11
publication date: 2025-05-11
starting page: 27
ending page: 28
doi: 10.3407/rpn.v6i1cp7

PP41 Antifungal Activity of Ethanolic Extract of Ripe Seeds from Azadirachta indica against Pestalotia sp in Coffee Leaf – Experimental Farm Pueblo Bello, Cesar
type: item
description: Coffee in Colombia is one of the agricultural products with the greatest social, industrial, and economic importance, reaching almost 70 countries and making it one of the most recognized and widely distributed Colombian products worldwide. This crop is affected by various fungal diseases that can impact productivity and cause economic losses [1].
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Hojas de café
  topic: keywords
subject: Azadirachta indica
  topic: keywords
subject: Pestalotia sp
  topic: keywords
subject: Semilla madura
  topic: keywords
subject: Actividad antifúngica
  topic: keywords
creator: Lenka Victoria Tamayo Lopez
creator: Diego Camilo Durán
creator: Aslenis Melo Ríos
creator: Pedro J. Fragoso-Castilla
creator: Anahy Desireth Rodriguez Ovalle
rights: Copyright (c) 2025 Lenka Victoria Tamayo Lopez, Diego Camilo Durán, Aslenis Melo Ríos, Pedro J. Fragoso-Castilla, Anahy Desireth Rodriguez Ovalle https://creativecommons.org/licenses/by/4.0
date: 2025-07-25
publication date: 2025-07-25
starting page: 336
ending page: 339
doi: 10.3407/a2qz2m67

PP55 Influence of microencapsulation on the stability and evaluation of the antimicrobial activity of essential oils from the Lamiaceae family
type: item
description: Skin infections, such as acne, are a common reason for dermatological consultations and are associated with pathogens like Staphylococcus aureus and Propionibacterium acnes. Although antimicrobials are used, bacterial resistance has spurred the search for alternatives, such as essential oils (EO), whose bioactive compounds possess antiseptic properties. However, their volatility limits their application, which is why microencapsulation emerges as a strategy to improve their stability. This study prioritized four plant species rich in monoterpenes and evaluated three microencapsulation methods. Both free and encapsulated EO demonstrated antibacterial activity, highlighting their potential in dermatological formulations.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: essential oils
  topic: keywords
subject: microencapsulation
  topic: keywords
subject: antimicrobial activity
  topic: keywords
creator: william patino
rights: Copyright (c) 2025 William Ramiro PATIÑO BAYONA, Sintia Juliet Garzon Restrepo https://creativecommons.org/licenses/by/4.0
date: 2025-07-22
publication date: 2025-07-22
starting page: 378
ending page: 379
doi: 10.3407/mbhwqt33

PO22 Larvicidal effect of hexane and ethyl acetate extracts of Austroeupatorium inulifolium on fourth-instar larvae of Aedes aegypti
type: item
description: The larvicidal, cytotoxic, and allelochemical effects of Austroeupatorium inulifolium extracts obtained with hexane and ethyl acetate were evaluated. Bioassays were conducted against fourth-instar larvae of Aedes aegypti, showing high efficacy of the ethyl acetate extract (lowest LD₅₀). Cytotoxicity in VERO cells was found to be non-toxic, and no significant allelochemical effects were observed in Lactuca sativa. GC-MS analysis identified compounds such as β-caryophyllene, phytol, and hexadecanoic acid. The results support the potential of this species as a source of bioactive compounds for biological vector control and integrated ecological management.
subject: Abstract
  topic: section
subject: Special Issues
  topic: category
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Aedes aegypti
  topic: keywords
subject: Austroeupatorium inulifolium
  topic: keywords
subject: larvicidal activity
  topic: keywords
creator: jorge ivan sierra acevedo
creator: Eunice Rios Vasquez
creator: Jaime Alberto Marin Colorado
rights: Copyright (c) 2025 M.Q. Jorge I. Sierra Acevedo, Dra. Eunice R, Vasquez, Dr. Jaime A. Marin Colorado https://creativecommons.org/licenses/by/4.0
date: 2025-05-21
publication date: 2025-05-21
starting page: 93
ending page: 95
doi: 10.3407/3sybrw26

PP36 Estudio del Potencial Inhibitorio sobre Lipasa Pancréatica de Algunos Componentes Químicos Provenientes de Piper asperiusculum (Piperaceae)
type: item
description: Pancreatic lipase (PL) is a key enzyme in lipid digestion and a widely studied therapeutic target for obesity treatment. Inhibition of PL reduces fat absorption and promotes weight loss; however, available drugs have limitations related to adverse effects and variable efficacy [1]. This situation has driven the search for safer natural alternatives, among which plants of the Piper genus (Piperaceae) known for their diversity of secondary metabolites, some of which can inhibit digestive enzymes such as PL [2].
subject: Abstract
  topic: section
subject: I Colombian Congress of Natural Products (2025)
  topic: category
subject: Obesidad
  topic: keywords
subject: lipasa pancreática
  topic: keywords
subject: piper asperiusculum
  topic: keywords
subject: piper
  topic: keywords
subject: cromenos
  topic: keywords
creator: Paula Alejandra Arguello Quevedo
creator: Oscar Javier Patiño Ladino
creator: Juliet Angélica Prieto Rodríguez
creator: Diego Alejandro Silva Carrero
rights: Copyright (c) 2026 Paula Alejandra Arguello Quevedo, Oscar Javier Patiño Ladino, Juliet Angélica Prieto Rodríguez, Diego Alejandro Silva Carrero https://creativecommons.org/licenses/by/4.0
date: 2026-01-21
publication date: 2026-01-21
starting page: 321
ending page: 323
doi: 10.3407/rpn.v6i1pp36