PO18 From the Cruz-Badiano Codex to the Study of Anxiolytic-Like Effects of Three Plants from Montanoa Genus
DOI:
https://doi.org/10.3407/d5mrk595Keywords:
Códice De La Cruz-Badiano, Montanoa futescens, Montanoa tomentosa, Montanoa grandiflora, Ansiolítico, Sistema GABAérgicoAbstract
The De la Cruz-Badiano Codex describes the use of three plants (M. tomentosa, M. frutescens, and M. grandiflora) for the treatment of emotional and affective disorders. This paper presents the results of different doses of crude aqueous extracts of the three plants related to anxiety in the Wistar rat. The three extracts exert anxiolytic effects in the elevated arm maze and the locomotor activity test, similar to diazepam, through actions on the GABA receptor. This supports a potential therapeutic effect of these plants for the treatment of anxiety.
References
[1] DE LA CRUZ-BADIANO Codex. (1552). Libellus de Medicinalibus Indorum Herbis. Disponible en: URL. Acceso: 25 de marzo de 2025.
[2] LEVINE, S.D., et al. (1981). The Mexican plant zoapatle (Montanoa tomentosa) in reproductive medicine. Past, present and future. Journal of Reproductive Medicine 26, 524–528.
[3] XIMENEZ, F. (1615). Quatro libros de la naturaleza y virtudes de las plantas y animales que están recevidos en el uso de medicina en la Nueva España, y la método, y corrección y preparación que para administrarllas se requiere con lo que el doctor Francisco Hernández escrivio en lengua latina. Viuda de Diego López Davalos, México. Disponible en: URL. Acceso: 25 de marzo de 2025.
[4] CARRO-JUÁREZ M. et al. (2012). The aqueous crude extract of Montanoa frutescens produces anxiolytic-like effects similarly to diazepam in Wistar rats: involvement of GABAA receptor. Journal of Ethnopharmacology, 143(2):592-8. [DOI].
[5] RODRÍGUEZ-LANDA J.F. (2014). Montanoa frutescens and Montanoa grandiflora extracts reduce anxiety-like behavior during the metestrus-diestrus phase of the ovarian cycle in Wistar rats. Biomed Research International, 2014:938060. [DOI].
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Copyright (c) 2025 Juan Francisco Rodríguez-Landa, María de Jesús Rovirosa-Hernández, Francisco García-Orduña
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