PP58 Biodirected Fractionation of Mammea Americana Seed Extract Through In Vitro Antimalarial Activity Against Plasmodium Falciparum Strain Fcb-2
DOI:
https://doi.org/10.3407/a1hk7994Keywords:
Malaria, antimalarials, Mammea Americana, Plasmodium falciparumAbstract
Malaria remains a public health problem in many countries, including Colombia. In 2023, the World Health Organization (WHO) reported 263 million cases of malaria worldwide [1]. In Colombia, by 2024, 123,740 cases were reported, leaving the country far from the WHO's goal of zero malaria [2].
Mammea americana is a tree from the Calophyllaceae family, which is used in Colombian ethnobotanical medicine to treat malaria [3]. There is not enough scientific evidence on the antimalarial activity of this species, therefore, the objective of this research was to determine the antimalarial activity of M. americana and its phytochemical profile.
References
[1] WORLD HEALTH ORGANIZATION. (2023). World Malaria Report 2023. WORLD HEALTH ORGANIZATION. URL
[2] PEDRAZA CALDERÓN, J. y BENAVIDES RUIZ, M. M. (2024). Informe De Evento Malaria 2023. INSTITUTO NACIONAL DE SALUD. URL
[3] MOSQUERA-CHAVERRA, L., et al. (2022). Ethnomedicinal Studies, Chemical Composition, and Antibacterial Activity of the Mammea Americana L. Bark in the Municipality of Cértegui, Chocó, Colombia. Advances in Pharmacological and Pharmaceutical Sciences 2022(1): 9950625. [DOI]
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Copyright (c) 2025 Andres David Centanaro Osorio, Fredyc Diaz-Castillo, Nicole Paola Arrieta Caldera, Carlos Moneriz Pretell
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