PP13 Bioactive Alkaloids from Two Amaryllidaceae Species: Cytotoxic Potential Against Gastric Cancer Cells
DOI:
https://doi.org/10.3407/85bd4r28Keywords:
Amaryllidaceae, Caliphruria subedentata, Phaedranassa lehmannii, Cytotoxic activity, Gastric cancerAbstract
Cancer is a significant health problem and one of the main causes of death in the world [1]. Chemotherapy is one of the most common treatments [2], and Amaryllidaceae alkaloids represent promising cytotoxic agents and potential chemotherapeutics against various types of cancer [3;4].
References
Cancer [Internet]. [cited 2025 Mar 28]. Available from: https://www.who.int/news-room/fact-sheets/detail/cancer
Treatment For Cancer | Cancer Treatment Options [Internet]. [cited 2025 Mar 28]. Available from: https://www.cancer.org/cancer/managing-cancer/treatment-types.html
Nair JJ, Van Staden J. The plant family Amaryllidaceae as a source of cytotoxic homolycorine alkaloid principles. South African Journal of Botany. 2021 Jan 1; 136:157–74.
Tallini LR, Machado das Neves G, Vendruscolo MH, Rezende-Teixeira P, Borges W, Bastida J, et al. Antitumoral activity of different Amaryllidaceae alkaloids: In vitro and in silico assays. Journal of Ethnopharmacology. 2024 Jul 15; 329:118154.
Lekhak MM, Patel SB, Otari SS, Lekhak UM, Ghane SG. Bioactive potential and RP-HPLC detection of phenolics and alkaloids (lycorine and galanthamine) from ultrasonic-assisted extracts of Crinum roots. South African Journal of Botany. 2022 Sep 1; 149:923–36.
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