PP73 Cytotoxic Potential of Doxorubicin and Amaryllidaceae Alkaloids in an In Vitro Model of Gastric Cancer
DOI:
https://doi.org/10.3407/v3aebk81Keywords:
Potencial citotóxico, cáncer gástrico, licorina, doxorrubicina.Abstract
Cancer is one of the leading causes of death worldwide, accounting for approximately 10 million deaths in 2022 [1]. Among the most common types of cancer globally, gastric cancer ranks as the fifth most prevalent. However, in Colombia, it stands out as the leading type of cancer in mortality, with approximately 57 thousand deaths in 2022 [2]. Despite significant advances in understanding the disease and developing treatments, cancer continues to be a challenge for the global scientific and medical community. Currently, various treatment alternatives are employed, among which chemotherapy is one of the fundamental pillars [3].
References
[1] ORGANIZACIÓN MUNDIAL DE LA SALUD. Cáncer. (2022). URL
[2] FERLAY, J., et al. Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. (2024). URL
[3] XUAN, W., et al. (2019). Drug Resistance and Combating Drug Resistance in Cancer. Cancer Drug Resistance 2(2): 141-160. [DOI]
[4] SEENEEVASSEN, L., et al. (2021). Gastric Cancer: Advances in Carcinogenesis Research and New Therapeutic Strategies. Int J Mol Sci 22(7). [DOI]
[5] ROY, M., et al. (2018). Lycorine: A Prospective Natural Lead for Anticancer Drug Discovery. Biomedicine & Pharmacotherapy 107: 615-624. [DOI]
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