PO22 Larvicidal effect of hexane and ethyl acetate extracts of Austroeupatorium inulifolium on fourth-instar larvae of Aedes aegypti
DOI:
https://doi.org/10.3407/3sybrw26Keywords:
Aedes aegypti, Austroeupatorium inulifolium, larvicidal activityAbstract
The larvicidal, cytotoxic, and allelochemical effects of Austroeupatorium inulifolium extracts obtained with hexane and ethyl acetate were evaluated. Bioassays were conducted against fourth-instar larvae of Aedes aegypti, showing high efficacy of the ethyl acetate extract (lowest LD₅₀). Cytotoxicity in VERO cells was found to be non-toxic, and no significant allelochemical effects were observed in Lactuca sativa. GC-MS analysis identified compounds such as β-caryophyllene, phytol, and hexadecanoic acid. The results support the potential of this species as a source of bioactive compounds for biological vector control and integrated ecological management.
References
[1] Alves, M. S., et al. (2024). Austroeupatorium inulifolium as a source of bioactive terpenoids: Larvicidal effects against Aedes aegypti and non-target toxicity assessment. Industrial Crops and Products, 208, 117892.
[2] Pavela, R., et al. (2023). Novel ethyl acetate extracts from Asteraceae: Phytochemical profiling and eco-friendly larvicidal activity against dengue and Zika vectors. Scientific Reports, 13, 18976.
[3] Gutiérrez-López, L. A., et al. (2023). Synergistic larvicidal effect of β-caryophyllene and phytol from Austroeupatorium spp. against resistant populations of Aedes aegypti. Parasites & Vectors, 16(1), 412.
[4] Silva, R. C., et al. (2024). Eco-friendly vector control: Allelopathic and cytotoxic effects of South American Asteraceae extracts on Aedes aegypti and non-target organisms. Ecotoxicology and Environmental Safety, 272, 116081.
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