PO34 Evaluation of the Anti-Aging Activity of Peptides Obtained by Enzymatic Hydrolysis with Actinidin from Colombian Quinoa Seed Proteins
DOI:
https://doi.org/10.3407/r69wyv10Keywords:
Peptides, quinoa, anti-aging activityAbstract
This study evaluated the anti-aging activity of peptides obtained through enzymatic hydrolysis of quinoa (Chenopodium quinoa) seed proteins, rich in lysine, using actinidin, a cysteine protease with affinity for this residue. Proteins were isolated and characterized using the bicinchoninic acid (BCA) assay and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), yielding a peptide extract with a degree of hydrolysis (DH) of 21.6%. Antioxidant activity (35%) and inhibition of collagenase (87.9%) and elastase (30.98%) were determined, demonstrating potential for skin protection. Accompanied by in silico analysis, further prediction of their antioxidant and inhibitory capacity supports applications in nutraceutical and cosmeceutical products.
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Copyright (c) 2025 Nicolas S. Caicedo Cerón, José Fernando Oñate Garzón, Yamil Liscano Martínez
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