PP42 Evaluation of the cytotoxic and antioxidant activity of oils derived from the fruit of seje (Oenocarpus bataua) in an in vitro model of human hepatocarcinoma
DOI:
https://doi.org/10.3407/rpn.v6i1pp42Keywords:
Antioxidants, Essential Oils, Reactive Oxygen Species, Oxidative StressAbstract
Antioxidants protect against oxidative stress caused by reactive oxygen species (ROS), whose excess damages biomolecules and promotes chronic diseases. The fruit of Oenocarpus bataua is rich in antioxidant compounds, but their activity may depend on the extraction method. In this study, the cytotoxic and antioxidant activities of oils extracted by Soxhlet (SOX) and supercritical fluid emulsion (SFC) were evaluated in HepG2 and L929 cells. The SFC emulsion showed higher cell viability but without antioxidant effect, whereas the SOX emulsion reduced ROS production. Thus, SOX oil is emerging as a promising source of antioxidant compounds.
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Copyright (c) 2026 Sara Gaitan Blanco, Juan Pablo BARRERO ECHEVERRÍA, Sandra Johanna MORANTES MEDINA, Diego BALLESTEROS VIVAS
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