PP57 Heterogeneous Photocatalysis with TiO2 for the Oxidation of Synthetic Lipids from Staphylococcus aureus: Optimization and Biophysical Implications
DOI:
https://doi.org/10.3407/rpn.v6i1pp57Keywords:
Heterogeneous Photocalysis, S. aureus, Oxidation, Biophysical Properties, Experiment of Design, MembraneAbstract
Oxidative stress affects the structure and function of bacterial membranes, influencing their stability and resistance. In this study, heterogeneous photocatalysis with TiO₂ was used to induce oxidation in synthetic lipids of Staphylococcus aureus. Through a design of experiments, hydroxyl radical generation was optimized, identifying TiO₂ concentration and agitation as key factors. The results showed changes in membrane rigidity and phase transition temperature, indicating structural alterations. These findings could contribute to the development of antimicrobial strategies and applications in biomedicine and environmental decontamination.
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Copyright (c) 2026 Juan Esteban Gonzalez Martinez, Dr. Chad Leidy, Dra. Chiara Carazzone

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