• Isolation, purification, and identification of natural products.
• Structural elucidation and spectroscopic analysis.
• Phytochemistry and pharmacognosy.
• Natural products from plants, fungi, microorganisms, and animals.
• Marine natural products.
• Chromatographic, spectroscopic, spectrometric, and other analytical methodologies.
• Quality control and quality assurance.
• Standardization and chemical characterization of natural materials.

• Evaluation of the biological activities of natural products and their derivatives.
• Pharmacology and mechanisms of action.
• Toxicology and safety assessment.
• Medicinal chemistry of natural products.
• Structure-activity relationships.
• Natural products and the discovery of bioactive candidates.
• In vitro, in vivo, and other relevant experimental models.

• Ethnobotany.
• Ethnopharmacology.
• Ethnoveterinary research.
• Traditional uses of natural resources.
• Pharmacognosy.
• Relationships among traditional knowledge, chemical composition, and biological activity.
• Scientific validation of traditional uses.
• Interdisciplinary research involving biodiversity, communities, and natural products.

• Biosynthesis of specialized metabolites.
• Biosynthetic enzymology.
• Biocatalysis.
• Fermentation.
• Cell and tissue culture.
• Biotransformations.
• Natural product biotechnology.
• Molecular biology.
• Metabolic engineering.
• Bioengineering and sustainable production of natural products.

• Total synthesis.
• Semisynthesis.
• Derivatization and chemical modification.
• Natural product analogues.
• Compounds inspired by natural product structures.
• Chemical and biocatalytic transformations.
• Relationships among structural modification, physicochemical properties, and biological activity.

RPN considers research at the interface between natural products and coordination chemistry, bioinorganic chemistry, and organometallic chemistry when there is a substantive scientific relationship with natural products, specialized metabolites, naturally occurring bioactive compounds, or structures inspired by them.

• Metal complexes of natural products or their derivatives.
• Interaction and coordination of specialized metabolites with metals.
• Modification of natural products through coordination or organometallic chemistry.
• Metallodrugs derived from, conjugated with, or inspired by natural products.
• Organic-metal hybrid systems of biological or medicinal interest.
• Catalytic, analytical, biological, or medicinal applications related to natural products.
• Relationships among metal coordination, structure, and bioactivity.

Studies in inorganic, coordination, or organometallic chemistry without a scientifically substantive relationship to natural products fall outside the scope of RPN.

• Metabolomics.
• Genomics, transcriptomics, and proteomics related to natural products.
• Integrative omics.
• Genome mining and discovery of biosynthetic gene clusters.
• Bioinformatics.
• Cheminformatics.
• Molecular networking and data analysis.
• Computational modelling.
• Machine learning and artificial intelligence applied to the discovery, characterization, or evaluation of natural products.

Predominantly computational studies must maintain a clear scientific relationship with natural products and make a verifiable contribution within the scope of RPN.

• Chemical ecology.
• Allelopathy.
• Chemotaxonomy.
• Ecological functions of specialized metabolites.
• Chemical organism-organism and organism-environment interactions.
• Chemical responses to stress and environmental factors.
• Ecology of natural products.
• Relevant environmental transformations of natural metabolites.

• Natural products in foods.
• Functional foods.
• Natural ingredients and food-derived bioactive compounds.
• Nutraceuticals.
• Nutritional and functional properties.
• Sensory evaluations related to chemical composition.
• Stability of bioactive compounds.
• Physical or chemical changes induced by processing, preservation, or storage.
• Development and characterization of functional products derived from biodiversity.

RPN considers research on the development and application of natural products in areas such as:

• Pharmaceutical products.
• Cosmetics and cosmeceuticals.
• Nutraceuticals.
• Foods and functional ingredients.
• Veterinary products.
• Agrochemicals, biological inputs, and agricultural products.
• Extraction, separation, transformation, and utilization technologies.
• Valorization of residues and by-products as sources of natural products.
• Green and sustainable processes.
• Scientifically responsible bioprospecting.
• Sustainable use of biodiversity.
• Bioeconomy based on biological resources.

Studies in coordination chemistry, bioinorganic chemistry, or organometallic chemistry are relevant when natural products, their derivatives, or structures inspired by them constitute a substantive scientific component of the research. Studies without this relationship fall outside the scope of RPN.

Computational, modelling, machine-learning, or artificial-intelligence studies are relevant when they directly address scientific questions involving natural products and make a verifiable contribution to knowledge within the scope of the journal.

Studies involving foods, nutraceuticals, natural ingredients, and functional products are relevant when natural products, their composition, activity, transformation, stability, or function constitute a central scientific element of the research.