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PP35 Antihypertensive potential of extracts pulp Theobroma grandiflorum amazonian fruit

Authors

  • Liceth Natalia Cuellar Alvarez Grupo de Investigación en Productos Naturales, Facultad de Ciencias Básicas, Universidad de la Amazonia https://orcid.org/0000-0003-0638-6998
  • Wilson RODRIGUEZ Grupo de Investigación en Productos Naturales Amazónicos- GIPRONAZ, Facultad de Ciencias Básicas, Universidad de la Amazonia, Florencia 180001, Colombia
  • Gloria M. PALADINES Grupo de Investigación en Productos Naturales Amazónicos- GIPRONAZ, Facultad de Ciencias Básicas, Universidad de la Amazonia, Florencia 180001, Colombia https://orcid.org/0000-0001-8252-4892

DOI:

https://doi.org/10.3407/dxzy0542

Keywords:

Theobroma grandiflorum; antihypertensive activity; polyphenols; Amazonian fruit.

Abstract

The objective of this study was to characterize, using liquid chromatography coupled with mass spectrometry analysis, together with the evaluation of the in vitro antihypertensive activity of the pulp of Copoazú fruits. The chromatographic profile of the extract obtained with ethyl acetate indicated the presence of polyphenols such as gallic acid, and other metabolites with biological potential. Likewise, the in vitro antihypertensive activity evaluated through the ACE-I enzyme inhibition assay showed that the extract enriched in ethyl acetate obtained a percentage of inhibition compared to another Amazonian fruit

Author Biography

  • Liceth Natalia Cuellar Alvarez, Grupo de Investigación en Productos Naturales, Facultad de Ciencias Básicas, Universidad de la Amazonia

    Liceth N. Cuéllar Álvarez is Associate Professor in the Chemistry Program at the Universidad de la Amazonia in Florencia, Caquetá, Colombia and Leader of the Research Group in Productos Naturales Amazónicos – GIPRONAZ. Her main line of research is Food Chemistry and elaboration of foods from Amazonian fruits.

References

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[3] BARROS, R. G. C., et al. (2017). Evaluation of Bioactive Compounds Potential and Antioxidant Activity in Some Brazilian Exotic Fruit Residues. Food Research International 102: 84-92. [DOI]

[4] BATAGLION, G. A., et al. (2015). Determination of the Phenolic Composition from Brazilian Tropical Fruits by Uhplc–Ms/Ms. Food Chemistry 180: 280-287. [DOI]

[5] DE SOUZA SCHMIDT GONÇALVES, A. E., et al. (2010). Chemical Composition and Antioxidant/Antidiabetic Potential of Brazilian Native Fruits and Commercial Frozen Pulps. Journal of Agricultural and Food Chemistry 58(8): 4666-4674. [DOI]

[6] GARCÍA-CHACÓN, J. M., et al. (2023). Camu Camu (Myrciaria Dubia (Kunth) Mcvaugh): An Amazonian Fruit with Biofunctional Properties–a Review. ACS Omega 8(6): 5169-5183. [DOI]

[7] ROGEZ, H., et al. (2004). Chemical Composition of the Pulp of Three Typical Amazonian Fruits: Araça-Boi (Eugenia Stipitata), Bacuri (Platonia Insignis) and Cupuaçu (Theobroma Grandiflorum). European Food Research and Technology 218(4): 380-384. URL [DOI]

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Published

2025-08-13 — Updated on 2025-07-21

Versions

How to Cite

Cuellar Alvarez, L. N., RODRIGUEZ, W., & PALADINES, G. M. . (2025). PP35 Antihypertensive potential of extracts pulp Theobroma grandiflorum amazonian fruit. Revista Productos Naturales, 6(1), 318-320. https://doi.org/10.3407/dxzy0542